Human L1CAM ELISA Kit sinobiological KIT10140
$714.00
In stock
SKU
KIT10140
| Catalog No. | Size | Price (USD) |
| KIT10140-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human L1CAM ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human CD171. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 10.8 pg/mL |
| Assay range | 39.06-2500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human L1CAM ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human L1CAM protein in Serum . It contains recombinant Human L1CAM, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: CAML1 ELISA Kit, Human; CD171 ELISA Kit, Human; HSAS ELISA Kit, Human; HSAS1 ELISA Kit, Human; HYCX ELISA Kit, Human; MASA ELISA Kit, Human; MIC5 ELISA Kit, Human; N-CAM-L1 ELISA Kit, Human; N-CAML1 ELISA Kit, Human; NCAM-L1 ELISA Kit, Human; S10 ELISA Kit, Human; SPG1 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human CD171/L1CAM ELISA Kit Standard Curve 17213 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human CD171/L1CAM ELISA Kit Specificity 17226 |
| Image 2 URL | Source image |
Background Information
| Full Name | L1 cell adhesion molecule |
| Description | L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait, and adducted thumbs), and spastic paraplegia syndrome. Overexpression of L1CAM in normal and cancer cells increased motility, enhanced growth rate, and promoted cell transformation and tumorigenicity. Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy. |
| References |
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