Rat MMP-9 ELISA Kit sinobiological KIT80049
$400.00
In stock
SKU
KIT80049
| Catalog No. | Size | Price (USD) |
| KIT80049-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Rat MMP-9 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Rat MMP9. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 5.5 pg/mL |
| Assay range | 31.25-2000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Rat MMP-9 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Rat MMP-9 protein in Serum . It contains recombinant Rat MMP-9, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the following factors at 50 ng/mL in a mid-range recombinant Rat MMP9 control were assayed for interference. No significant interference was observed. |
Synonyms: Mmp9 ELISA Kit, Rat
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Rat MMP9/MMP-9/CLG4B ELISA Kit Standard Curve 15930 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Rat MMP9/MMP-9/CLG4B ELISA Kit Specificity 15939 |
| Image 2 URL | Source image |
Background Information
| Full Name | matrix metallopeptidase 9 |
| Description | Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutrophils, macrophages, and some transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. It plays an important role in tissue remodeling in normal and pathological inflammatory processes. MMP-9 is a major secretion product of macrophages and a component of cytoplasmic granules of neutrophils and is particularly important in the pathogenesis of inflammatory, infectious, and neoplastic diseases in many organs including the lung. This enzyme is also secreted by lymphocytes and stromal cells upon stimulation by inflammatory cytokines, or upon delivery of bi-directional activation signals following integrin-mediated cell-cell or cell-extracellular matrix (ECM) contacts. Since the integrity of the tissue architecture is closely dependent on the delicate balance between MMPs and their inhibitors, excessive production of MMP-9 is linked to tissue damage and degenerative inflammatory disorders. As a consequence, regulation of gene transcription and tissue-specific expression of MMP-9 in normal and diseased states are being actively investigated to pave the way for new therapeutic targets. Besides, the dramatic overexpression of MMP-9 in cancer and various inflammatory conditions points to the molecular mechanisms controlling its expression as a potential target for eventual rational therapeutic intervention. |
| Research Areas |
|
| Related Pathways |
|
| References |
|
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
