Human NOV/CCN3 ELISA Kit sinobiological KIT10264
$714.00
In stock
SKU
KIT10264
| Catalog No. | Size | Price (USD) |
| KIT10264-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human NOV/CCN3 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human NOV. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 55.91 pg/mL |
| Assay range | 93.75-6000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human NOV/CCN3 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human NOV/CCN3 protein in Serum . It contains recombinant Human NOV/CCN3, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human CCN3 / NOV (IGFBP9) ELISA Kit Standard Curve 54 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human CCN3 / NOV (IGFBP9) ELISA Kit Specificity 203 |
| Image 2 URL | Source image |
Background Information
| Full Name | nephroblastoma overexpressed |
| Description | Protein NOV homolog, also known as Nephroblastoma-overexpressed gene protein homolog, NOV, and CCN3, is a putative ligand for integrin receptors, is tightly associated with the extracellular matrix, and mediates diverse cellular functions, including cell adhesion and proliferation. CCN3 has been shown to negatively regulate growth although it promotes migration in a cell type-specific manner. This secreted protein belongs to the CCN family, and its expression was observed in a broad variety of tissues from the early stage of development, and altered expression of CCN3 has been observed in a variety of tumors, including hepatocellular carcinomas, Wilm's tumors, Ewing's sarcomas, gliomas, rhabdomyosarcomas, and adrenocortical carcinomas. Mature CCN3 protein has five distinct modules and truncated protein variants with altered function are found in many cancers. CCN3 acts through the core stem cell signaling pathways including Notch and Bone Morphogenic Protein, connecting CCN3 with the modulation of self-renewal and maturation of some cell lineages including hematopoietic, osteogenic, and chondrogenic. CCN3 may affect the extracellular environment of the niche for hematopoietic stem cells. CCN3 has emerged as a key player in stem cell regulation, hematopoiesis, and a crucial component within the bone marrow microenvironment. |
| References |
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