| Catalog No. | Size | Price (USD) |
| 50129-R004-20 | 20 µL | $118.49 |
| 50129-R004-50 | 50 µL | $222.17 |
| 50129-R004-100 | 100 µL | $370.28 |
General Information
| Product name | Recombinant Anti-CD204/MSR1 Antibody, Rabbit Monoclonal |
| Validated applications | IHC-P (FAQ Protocol), FCM (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse CD204/MSR1 |
| Immunogen | Recombinant Mouse MSR1 / CD204 protein (Catalog#50129-M07H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; Catalog#50129-M07H; AAH03814.1; Trp 83-Val 354). |
| Source | Monoclonal Rabbit IgG Clone #004 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MRS-A Antibody; Anti-MSR Antibody; Anti-MSR-A Antibody; Anti-Msr1 Antibody; Anti-Scara1 Antibody; Anti-Scvr Antibody; Anti-SR-A Antibody; Anti-SR-AI Antibody; Anti-SR-AII Antibody
Image / Experimental Information
| Image 1 Description | Confocal immunofluorescence analysis of Mouse MSR1 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse MSR1 monoclonal antibody (1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. |
| Image 1 Alt Text | Mouse MSR1/CD204 Immunohistochemistry(IHC) 5473 |
| Image 1 URL | Source image |
| Image 2 Description | Confocal immunofluorescence analysis of Mouse MSR1 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse MSR1 monoclonal antibody (1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. |
| Image 2 Alt Text | Mouse MSR1/CD204 Immunohistochemistry(IHC) 14782 |
| Image 2 URL | Source image |
| Image 3 Description | Confocal immunofluorescence analysis of Mouse MSR1 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse MSR1 monoclonal antibody (1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane. |
| Image 3 Alt Text | Mouse MSR1/CD204 Flow Cytometry (FC) 14790 |
| Image 3 URL | Source image |
Background Information
| Full Name | macrophage scavenger receptor 1 |
| Description | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
| References |
|
title: Rifamycin analogs and antibody-drug conjugates thereof
authors: Thomas Nittoli; Seungyong Sean Choi; Mrinmoy Saha
date: 2023-06-06
cited_by_count: 0
techniques: Binding Assay; Blocking Assay; Control; Expressing; Flow Cytometry; Incubation; Negative Control; Positive Control; Software; Staining
bioz_score: 93
title: Anti-MSR1 antibodies and methods of use thereof
authors: Jesper Gromada; Viktoria Gusarova; ...; Anna Zumsteg
date: 2022-07-05
cited_by_count: 0
techniques: Binding Assay; Blocking Assay; Expressing; Flow Cytometry; Incubation; Negative Control; Positive Control; Software; Staining
bioz_score: 92
title: Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development
authors: Tamihiro Kamata; Tsz Y. So; ...; Catrin Pritchard
journal: Cell Reports
date: 2020-06-23
pmid: 32579928
doi: 10.1016/j.celrep.2020.107802
pmcid: 7326292
cited_by_count: 28
techniques: Enzyme-linked Immunosorbent Assay; Imaging; Mass Spectrometry; Multiplex Assay; Plasmid Preparation; Recombinant; Software
bioz_score: 93
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