| Catalog No. | Size | Price (USD) |
| 50110-R034-50 | 50 µL | $177.58 |
| 50110-R034-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-CD27/TNFRSF7 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse CD27/TNFRSF7 No cross-reactivity in ELISA with Human CD27 Human TNFRSF8 Human CD40 Human DR6 Human TNFRSF10D Mouse HVEM Mouse FAS Mouse TNFRSF10b Human 4-1BB Human TNFRI Human BAFF Human TNFRII Human RELT |
| Immunogen | Recombinant Mouse CD27 protein (Catalog#50110-M08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD27 (rM CD27; Catalog#50110-M08H; NP_001028298.1; Met 1-Arg 182). |
| Source | Monoclonal Rabbit IgG Clone #034 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Cd27 Antibody; Anti-S152 Antibody; Anti-Tnfrsf7 Antibody; Anti-Tp55 Antibody
Background Information
| Full Name | CD27 molecule |
| Description | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis. |
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