Human L-selectin/CD62L ELISA Kit sinobiological KIT11838
$400.00
In stock
SKU
KIT11838
| Catalog No. | Size | Price (USD) |
| KIT11838-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human L-selectin/CD62L ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human SELL. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 2.41 pg/mL |
| Assay range | 12.5-800 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human L-selectin/CD62L ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human L-selectin/CD62L protein in Serum . It contains recombinant Human L-selectin/CD62L, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: CD62L ELISA Kit, Human; hLHRc ELISA Kit, Human; LAM-1 ELISA Kit, Human; LAM1 ELISA Kit, Human; LECAM1 ELISA Kit, Human; Leu-8 ELISA Kit, Human; LEU8 ELISA Kit, Human; LNHR ELISA Kit, Human; LSEL ELISA Kit, Human; Lyam-1 ELISA Kit, Human; LYAM1 ELISA Kit, Human; PLNHR ELISA Kit, Human; TQ1 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human CD62L/L-Selectin ELISA Kit Standard Curve 14511 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human CD62L/L-Selectin ELISA Kit Specificity 14527 |
| Image 2 URL | Source image |
Background Information
| Full Name | selectin L |
| Description | L-selectin (SELL), also known as CD62L, is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues. It belongs to the selectin family of proteins, and consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. L-selectin is the only selectin expressed on leukocytes and mediates a number of leukocyte-endothelial interactions. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point. L-selectin-mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. In addition, L-selectin-mediated entry into peripheral lymph nodes is required for optimal induction of lymphocyte homeostatic proliferation during lymphopenia. Importantly, L-selectin has been shown to have both adhesive and signaling functions during leukocyte migration. L-selectin has also been shown to mediate leukocyte recruitment during chronic inflammatory and autoimmune diseases and thus is a potential therapeutic target for drug development. |
| References |
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