Human SerpinA3 ELISA Kit sinobiological KIT10307
$714.00
In stock
SKU
KIT10307
| Catalog No. | Size | Price (USD) |
| KIT10307-1 | 1 KIT (96 Tests) | $740.55 |
General Information
| Product name | Human SerpinA3 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human SERPINA3. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 12.07 pg/mL |
| Assay range | 39.06-2500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human SerpinA3 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human SerpinA3 protein in Serum . It contains recombinant Human SerpinA3, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: AACT ELISA Kit, Human; ACT ELISA Kit, Human; GIG24 ELISA Kit, Human; GIG25 ELISA Kit, Human; SERPINA3 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human SerpinA3 ELISA Kit Standard Curve 11 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human SerpinA3 ELISA Kit Specificity 199 |
| Image 2 URL | Source image |
Background Information
| Full Name | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| Description | SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzyme is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Besides, ACT gene polymorphism has been implicated with Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), as well as stroke, since SerpinA3 is a major constituent of the plaques in AD and an inhibitor of amyloid beta peptide degradation. |
| References |
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