Human Alpha 2 Antiplasmin/SerpinF2 ELISA Kit sinobiological KIT10297
$714.00
In stock
SKU
KIT10297
| Catalog No. | Size | Price (USD) |
| KIT10297-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human Alpha 2 Antiplasmin/SerpinF2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human SERPINF2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 1.89 pg/mL |
| Assay range | 46.88-3000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human Alpha 2 Antiplasmin/SerpinF2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Alpha 2 Antiplasmin/SerpinF2 protein in Serum . It contains recombinant Human Alpha 2 Antiplasmin/SerpinF2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: A2AP ELISA Kit, Human; AAP ELISA Kit, Human; ALPHA-2-PI ELISA Kit, Human; alpha2AP ELISA Kit, Human; API ELISA Kit, Human; PLI ELISA Kit, Human; SERPINF2 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human SerpinF2 ELISA Kit Standard Curve 57 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human SerpinF2 ELISA Kit Specificity 197 |
| Image 2 URL | Source image |
Background Information
| Full Name | serpin peptidase inhibitor, clade F, member 2 |
| Description | SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of trypsin and chymotrypsin. This protease is produced mainly by liver and kidney, and also expressed in muscle, intestine, central nervous system, and placenta at a moderate level. It is indicated that Serpin F2 is a key regulator of plasmin-mediated proteolysis in these tissues. Alpha-2 AP is an unusual serpin in that it contains extensive N- and C-terminal sequences flanking the serpin domain. The N-terminal sequence is crosslinked to fibrin by factor XIIIa, whereas the C-terminal region mediates the initial interaction with plasmin. SerpinF2 is one of the inhibitors of fibrinolysis, which acts as the primary inhibitor of plasmin(ogen). It is a specific plasmin inhibitor, and is important in modulating the effectiveness and persistence of fibrin with respect to its susceptibility to digestion and removal by plasmin. Alpha-2 AP plays the dominant role in inhibiting both plasma clot lysis and thrombus lysis, and accordingly, the congenital deficiency of Alpha-2 antiplasmin causes a rare bleeding disorder because of increased fibrinolysis. Thus, it may be a useful target for developing more effective treatment of thrombotic diseases. |
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