Human SLAM/CD150 ELISA Kit sinobiological KIT10837

$400.00
In stock
SKU
KIT10837
Catalog No.SizePrice (USD)
KIT10837-11 Kit (96 Tests)$414.71

General Information

Product nameHuman SLAM/CD150 ELISA Kit
SpecificityThis assay recognizes recombinant human SLAMF1.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeRecombinant protein
Sensitivity1.4 pg/mL
Assay range8.59-550 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human SLAM/CD150 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human SLAM/CD150 protein in Recombinant protein . It contains recombinant Human SLAM/CD150, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of SH2D1A、ARF5、ANTXR1、PTPRC、LGALS1 and GK at 7 ng/mL in a mid-range recombinant human SLAMF1 control were assayed for interference. No significant interference was observed.

Synonyms: CD150 ELISA Kit, Human; CDw150 ELISA Kit, Human; SLAM ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman CD150 / SLAM / SLAMF1 ELISA Kit Standard Curve 82
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman CD150 / SLAM / SLAMF1 ELISA Kit Specificity 152
Image 2 URLSource image

Background Information

Full Namesignaling lymphocytic activation molecule family member 1
DescriptionCD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.
Research Areas
  • ITIM/ITAM Immunoreceptors and Related Molecules
References
  1. Tatsuo H, et al. (2002) The morbillivirus receptor SLAM (CD150). Microbiol Immunol. 46(3): 135-42.
  2. Sidorenko SP, et al. (2003)The dual-function CD150 receptor subfamily: the viral attraction. Nat Immunol. 4(1): 19-24.
  3. Yurchenko MY, et al. (2010) CD150 regulates JNK1/2 activation in normal and Hodgkin's lymphoma B cells. Immunol Cell Biol. 88(5): 565-74.
  4. Leonard VH, et al. (2010) Measles virus selectively blind to signaling lymphocytic activation molecule (SLAM ; CD150) is attenuated and induces strong adaptive immune responses in rhesus monkeys. J Virol. 84(7): 3413-20.

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