Human Lymphotoxin alpha/TNF beta ELISA Kit sinobiological KIT10270
$400.00
In stock
SKU
KIT10270
| Catalog No. | Size | Price (USD) |
| KIT10270-1 | 1 Kit (96 Tests) | $414.71 |
| Catalog No. | Size | Price (USD) |
| KIT10270-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human Lymphotoxin alpha/TNF beta ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human TNFβ. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Cell supernatant |
| Sensitivity | 0.9 pg/mL |
| Assay range | 7.8-500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human Lymphotoxin alpha/TNF beta ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Lymphotoxin alpha/TNF beta protein in Cell supernatant . It contains recombinant Human Lymphotoxin alpha/TNF beta, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the following factors at 50 ng/mL in a mid-range recombinant Human TNFβ control were assayed for interference. No significant interference was observed. |
Synonyms: LT ELISA Kit, Human; TNFB ELISA Kit, Human; TNFSF1 ELISA Kit, Human; TNLG1E ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human TNF-beta/TNFSF1/Lymphotoxin alpha ELISA Kit Standard Curve 17207 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human TNF-beta/TNFSF1/Lymphotoxin alpha ELISA Kit Specificity 17221 |
| Image 2 URL | Source image |
Background Information
| Full Name | lymphotoxin alpha |
| Description | Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. |
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