Human Von Willebrand Factor/vWF ELISA Kit sinobiological KIT10973

$714.00
In stock
SKU
KIT10973
Catalog No.SizePrice (USD)
KIT10973-11 Kit (96 Tests)$740.55

General Information

Product nameHuman Von Willebrand Factor/vWF ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human VWF.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity28.11 pg/mL
Assay range125-8000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human Von Willebrand Factor/vWF ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Von Willebrand Factor/vWF protein in Serum . It contains recombinant Human Von Willebrand Factor/vWF, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: F8VWF ELISA Kit, Human; VWD ELISA Kit, Human; VWF ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman VWF/Von Willebrand Factor ELISA Kit Standard Curve 91
Image 1 URLSource image

Background Information

Full Namevon Willebrand factor
DescriptionVon Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.
References
  1. Sadler JE. (1998) Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem, 67: 395-424.
  2. Batlle J, et al. (2009) Von Willebrand factor/factor VIII concentrates in the treatment of von Willebrand disease. Blood Coagul Fibrinolysis. 20(2):89-100.
  3. Sadler JE. (2009) von Willebrand factor assembly and secretion. J Thromb Haemost. 7 Suppl 1:24-7.
  4. Auton M, et al. (2010) The mechanism of VWF-mediated platelet GPIbalpha binding. Biophys J. 99(4):1192-201.
  5. Bowen DJ. (2010) Sugar targets VWF for the chop. Blood. 115(13):2565.
  6. Lpez JA, et al. (2010) VWF self-association: more bands for the buck. Blood. 116(19):3693-4.

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