| Catalog No. | Size | Price (USD) |
| 14683-RP01-100 | 100 µL | $147.96 |
| 14683-RP01-200 | 200 µL | $251.64 |
| 14683-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-CSEN Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CSEN |
| Immunogen | Recombinant Human CSEN / calsenilin / KCNIP3 protein (Catalog#14683-H07E) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CSEN / calsenilin / KCNIP3 (rh KCNIP3; Catalog#14683-H07E; Q9Y2W7-1; Met1-Ile256). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CSEN Antibody; Anti-DREAM Antibody; Anti-KCHIP3 Antibody
Background Information
| Full Name | Kv channel interacting protein 3, calsenilin |
| Description | KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. CSEN also functions as a calcium-regulated transcriptional repressor and interacts with presenilins. CSEN binds to the DRE element of genes including PDYN and FOS. CSEN is broadly expressed in the brain, thyroid, and other tissues. Diseases associated with KCNIP3 include Alzheimer's Disease and Niemann-Pick Disease, Type C2. |
| References |
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