Anti-CXCL11 Antibody, Mouse Monoclonal sinobiological 10876-MM12

$143.00
In stock
SKU
10876-MM12
Catalog No.SizePrice (USD)
10876-MM12-5050 µL$147.96
10876-MM12-100100 µL$251.64
10876-MM12-200200 µL$355.32

General Information

Product nameAnti-CXCL11 Antibody, Mouse Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CXCL11
ImmunogenRecombinant Human I-TAC / CXCL11 Protein (Catalog#10876-HNAE)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human I-TAC / CXCL11 (rh I-TAC / CXCL11; Catalog#10876-HNAE; O14625; Phe22-Phe94). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG2a Clone #12
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-b-R1 Antibody; Anti-H174 Antibody; Anti-I-TAC Antibody; Anti-IP-9 Antibody; Anti-IP9 Antibody; Anti-ITAC Antibody; Anti-SCYB11 Antibody; Anti-SCYB9B Antibody

Background Information

Full Namechemokine (C-X-C motif) ligand 11
DescriptionI-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
References
  1. Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
  2. Rani MR, et al. (2002) Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene. J Biol Chem. 277(41): 38456-61.
  3. Salmaggi A, et al. (2003) Expression and modulation of IFN-gamma-inducible chemokines (IP-10, Mig, and I-TAC) in human brain endothelium and astrocytes: possible relevance for the immune invasion of the central nervous system and the pathogenesis of multiple sclerosis. J Interferon Cytokine Res. 22(6):631-40.

Reviews

Write Your Own Review
You're reviewing:Anti-CXCL11 Antibody, Mouse Monoclonal sinobiological 10876-MM12
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.