Recombinant Anti-Cystatin D Antibody, Rabbit Monoclonal sinobiological 10506-R011

$171.00
In stock
SKU
10506-R011
Catalog No.SizePrice (USD)
10506-R011-5050 µL$177.58
10506-R011-100100 µL$340.51

General Information

Product nameRecombinant Anti-Cystatin D Antibody, Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Cystatin D No cross-reactivity in ELISA with Human FetuinA Mouse AHSG Human CST3
ImmunogenRecombinant Human Cystatin D / CST5 protein (Catalog#10506-H08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human Cystatin D / CST5 (rh Cystatin D / CST5; Catalog#10506-H08H; NP_001891.2; Met1-Val142).
SourceMonoclonal Rabbit IgG Clone #011
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Background Information

Full Namecystatin D
DescriptionCystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. As a member of type 2 cystatin, cystatin D is a single-domain protein and also has cysteine residues that form disulfide bridges. In contrast with the wider distribution of all the other family 2 cystatins, cystatin D is tissue-restricted expressed and has been found only in saliva and tears. and meanwhile, it displays an inhibition profile with a preferential inhibition on cathepsin S, H, L. Although the exact functions are largely unknown, it has reported that cystatin D is involved in the inhibition of virus replication and apoptosis.
References
  1. Freije J.P., et al. ,(1991), Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor. J. Biol. Chem. 266:20538-20543.
  2. Freije J.P., et al. , (1993), Human cystatin D. cDNA cloning, characterization of the Escherichia coli expressed inhibitor, and identification of the native protein in saliva.J. Biol. Chem. 268:15737-15744.
  3. Deloukas P., et al. ,(2001), The DNA sequence and comparative analysis of human chromosome 20.Nature 414:865-871.

title: Accurately identifying saliva from samples mixed with citric acid-containing beverages by indirect ELISA-based detection of cystatin D.
authors: Mana Nagata; Jun Ohta; ...; Koichi Sakurada
journal: Journal of forensic sciences
date: 2026-01-05
pmid: 41088558
doi: 10.1111/1556-4029.70197
cited_by_count: 0
bioz_score: 94

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