| Catalog No. | Size | Price (USD) |
| 10636-T16-50 | 50 µL | $147.96 |
| 10636-T16-100 | 100 µL | $251.64 |
| 10636-T16-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Fractalkine/CX3CL1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Fractalkine/CX3CL1 |
| Immunogen | Recombinant Human Fractalkine / CX3CL1 Protein (Catalog#10636-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Fractalkine / CX3CL1 (rh Fractalkine / CX3CL1; Catalog#10636-H08H; NP_002987.1; Met1-Arg339). Fractalkine / CX3CL1 specific IgG was purified by Human Fractalkine / CX3CL1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-A-152E5.2 Antibody; Anti-ABCD-3 Antibody; Anti-C3Xkine Antibody; Anti-CXC3 Antibody; Anti-CXC3C Antibody; Anti-FKN Antibody; Anti-fractalkine Antibody; Anti-neurotactin Antibody; Anti-NTN Antibody; Anti-NTT Antibody; Anti-SCYD1 Antibody
Background Information
| Full Name | chemokine (C-X3-C motif) ligand 1 |
| Description | Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines. |
| Research Areas |
|
| References |
|
