Anti-CAPRIN1 Antibody, Rabbit Polyclonal sinobiological 204396-T08
$243.00
In stock
SKU
204396-T08
| Catalog No. | Size | Price (USD) |
| 204396-T08-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CAPRIN1 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CAPRIN1 |
| Immunogen | E. coli-derived Human GPIP137/CAPRIN1 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human GPIP137/CAPRIN1 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-caprin-1 Antibody; Anti-CONDCAC Antibody; Anti-GPIAP1 Antibody; Anti-GPIP137 Antibody; Anti-GRIP137 Antibody; Anti-M11S1 Antibody; Anti-NEDLAAD Antibody; Anti-p137GPI Antibody; Anti-RNG105 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CAPRIN1 in human brain with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human GPIP137/CAPRIN1 Immunohistochemistry(IHC) 41517 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CAPRIN1 in human brain with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human GPIP137/CAPRIN1 Immunohistochemistry(IHC) 41518 |
| Image 2 URL | Source image |
Background Information
| Description | Cytoplasmic activation/proliferation-associated protein-1 (caprin-1) is an RNA-binding protein that participates in the regulation of cell cycle control-associated genes. Caprin-1 acts alone or in combination with other RNA-binding proteins, such as RasGAP SH3-domain-binding protein 1 and fragile X mental retardation protein. In the tumorigenesis process, caprin-1 primarily functions by activating cell proliferation and upregulating the expression of immune checkpoint proteins. Through the formation of stress granules, caprin-1 is also involved in the process by which tumor cells adapt to adverse conditions, which contributes to radiation and chemotherapy resistance. |
| References |
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