Anti-GSS/Glutathione Synthetase Antibody, Rabbit Polyclonal sinobiological 108030-T08

$143.00
In stock
SKU
108030-T08
Catalog No.SizePrice (USD)
108030-T08-5050 µL$147.96
108030-T08-100100 µL$251.64
108030-T08-200200 µL$355.32

General Information

Product nameAnti-GSS/Glutathione Synthetase Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GSS/Glutathione Synthetase
ImmunogenA synthetic peptide corresponding to the center region of the Human GSS/Glutathione Synthetase
PreparationProduced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human GSS/Glutathione Synthetase, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GSHS Antibody; Anti-HEL-S-64p Antibody; Anti-HEL-S-88n Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human GSS in human kidney with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman GSS/Glutathione Synthetase Immunohistochemistry(IHC) 19482
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human GSS in human kidney with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman GSS/Glutathione Synthetase Immunohistochemistry(IHC) 19483
Image 2 URLSource image

Background Information

Full Nameglutathione synthetase
DescriptionGSS (Glutathione Synthetase) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. GSS belongs to the eukaryotic GSH synthase family. Diseases associated with GSS include Glutathione Synthetase Deficiency and Glutathione Synthetase Deficiency Of Erythrocytes, Hemolytic Anemia Due To. Glutathione synthetase deficiency (GSSD) is a rare inborn error of glutathione metabolism with autosomal recessive inheritance. The severe form of the disease is characterized by acute metabolic acidosis, usually present in the neonatal period with hemolytic anemia and progressive encephalopathy.

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