| Catalog No. | Size | Price (USD) |
| 10332-R022-1 | 1 mL | $1,969.87 |
| 10332-R022-20 | 20 µL | $118.49 |
| 10332-R022-50 | 50 µL | $177.58 |
| 10332-R022-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-ICAM-2/CD102 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ICAM-2/CD102 |
| Immunogen | Recombinant Human ICAM-2/CD102 Protein (Catalog#10332-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human ICAM-2/CD102 (rh ICAM-2/CD102; Catalog#10332-H08H; NP_000864.2; Met1-Gln223). |
| Source | Monoclonal Rabbit IgG Clone #022 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD102 Antibody
Background Information
| Full Name | intercellular adhesion molecule 2 |
| Description | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
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