| Catalog No. | Size | Price (USD) |
| 13100-MM01-1 | 1 mL | $1,377.43 |
| 13100-MM01-20 | 20 µL | $118.49 |
| 13100-MM01-50 | 50 µL | $222.17 |
| 13100-MM01-100 | 100 µL | $370.28 |
General Information
| Product name | Anti-IGFBP7 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol), ELISA(Det) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IGFBP7 No cross-reactivity in ELISA with Human IGFBP3 Human IGFBP4 Human IGFBP6 Human cell lysate (293 cell line) |
| Immunogen | Recombinant Human IGFBP7 protein (Catalog#13100-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IGFBP7 (rh IGFBP7; Catalog#13100-H08H; Q16270; Met 1-Leu 282). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #01 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, 0.02% Tween 80, pH 6.0 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AGM Antibody; Anti-FSTL2 Antibody; Anti-IBP-7 Antibody; Anti-IGFBP-7 Antibody; Anti-IGFBP-7v Antibody; Anti-IGFBPRP1 Antibody; Anti-MAC25 Antibody; Anti-PSF Antibody; Anti-RAMSVPS Antibody; Anti-TAF Antibody
Background Information
| Full Name | insulin-like growth factor binding protein 7 |
| Description | Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| References |
|
title: An IGFBP7 hi endothelial cell subset drives T cell extravasation in psoriasis via endothelial glycocalyx degradation
authors: Qingyang Li; Shuai Shao; ...; Gang Wang
journal: The Journal of Clinical Investigation
date: 2023-05-01
pmid: 36917196
doi: 10.1172/JCI160451
pmcid: 10145935
cited_by_count: 16
techniques: Control; Knockdown; Transfection; Western Blot
bioz_score: 91
