Anti-IL-19 Antibody, Rabbit Polyclonal sinobiological 13089-RP01

$143.00
In stock
SKU
13089-RP01
Catalog No.SizePrice (USD)
13089-RP01-100100 µL$147.96
13089-RP01-200200 µL$251.64
13089-RP01-400400 µL$355.32

General Information

Product nameAnti-IL-19 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IL-19
ImmunogenRecombinant Human IL19 / Interleukin-19 protein (Catalog#13089-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human IL19 / Interleukin-19 (rh IL19; Catalog#13089-H08H; AAF06663.1; Met1-Ala177). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-IL-10C Antibody; Anti-IL-19 Antibody; Anti-MDA1 Antibody; Anti-NG.1 Antibody; Anti-ZMDA1 Antibody

Background Information

Full Nameinterleukin 19
DescriptionThe molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.

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