| Catalog No. | Size | Price (USD) |
| 11038-T08-50 | 50 µL | $147.96 |
| 11038-T08-100 | 100 µL | $251.64 |
| 11038-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Insulin Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Insulin |
| Immunogen | Recombinant Human Insulin / INS Protein (Catalog#11038-HNAY) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Insulin / INS (rh Insulin / INS; Catalog#11038-HNAY; P01308; Phe25-Lys53 & Gly90-Asn110). Insulin / INS specific IgG was purified by Human Insulin / INS affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IDDM Antibody; Anti-IDDM1 Antibody; Anti-IDDM2 Antibody; Anti-ILPR Antibody; Anti-IRDN Antibody; Anti-MODY10 Antibody; Anti-PNDM4 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human Insulin in human pancreas with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human Insulin / INS Immunohistochemistry(IHC) 15041 |
| Image 1 URL | Source image |
Background Information
| Full Name | insulin |
| Description | INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia. |
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