Anti-Lactoferrin/LTF Antibody, Rabbit Polyclonal sinobiological 11096-RP01

$143.00
In stock
SKU
11096-RP01
Catalog No.SizePrice (USD)
11096-RP01-100100 µL$147.96
11096-RP01-200200 µL$251.64
11096-RP01-400400 µL$355.32

General Information

Product nameAnti-Lactoferrin/LTF Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Lactoferrin/LTF
ImmunogenRecombinant Human Lactotransferrin / LTF protein (Catalog#11096-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human Lactotransferrin / LTF (rh LTF; Catalog#11096-H08H; P02788; Met1-Lys710). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GIG12 Antibody; Anti-HEL110 Antibody; Anti-HLF2 Antibody; Anti-LF Antibody

Background Information

Full Namelactotransferrin
DescriptionLactotransferrin, also known as Lactoferrin, Talalactoferrin, and LTF, is a secreted protein that belongs to the transferrin family. Transferrins are iron binding transport proteins that can bind two Fe ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B, and C have opioid antagonist activity. Lactoferrin A shows a preference for mu-receptors, while lactoferricin B and lactoferricin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Lactoferrin / LTF is a globular glycoprotein that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin / LTF is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin / LTF can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk. Lactoferrin / LTF is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucose. In particular, lactoferrin provides an antibacterial activity to human infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.
References
  1. Sánchez L, et al.,1992, Arch. Dis. Child. 67 (5): 657 - 61.
  2. Wakabayashi H, et al., 2000, J. Antimicrob. Chemother. 46 (4): 595-602.
  3. Nozaki A, et al., 2003, J. Biol. Chem. 278 (12): 10162-73.
  4. Azzam HS, et al., 2007, Liver Int. 27 (1): 17-25.

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