| Catalog No. | Size | Price (USD) |
| 104208-T08-50 | 50 µL | $147.96 |
| 104208-T08-100 | 100 µL | $251.64 |
| 104208-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-LAPTM4A Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Rat |
| Specificity | Human, Rat Mouse, Cynomolgus (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the center region of the Human LAPTM4A |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human LAPTM4A, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-HUMORF13 Antibody; Anti-KIAA0108 Antibody; Anti-LAPTM4 Antibody; Anti-MBNT Antibody; Anti-Mtrp Antibody; Anti-UNQ1846/PRO3574 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining LAPTM4A in human bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human LAPTM4A Immunohistochemistry(IHC) 19915 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining LAPTM4A in human bladder with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human LAPTM4A Immunohistochemistry(IHC) 19916 |
| Image 2 URL | Source image |
Background Information
| Full Name | lysosomal protein transmembrane 4 alpha |
| Description | LAPTM4A (Lysosomal Protein Transmembrane 4 Alpha) is a Protein Coding gene. This gene encodes a protein that has four predicted transmembrane domains. It belongs to the LAPTM4/LAPTM5 transporter family. Studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. Screening within a mating-based split-ubiquitin-yeast-two-hybrid system (mBSUS) revealed the LAPTM4A as a potential interacting protein. Interaction of LAPTM4A and hOCT2 was confirmed by pulldown assays, FRET microscopy analysis, and immunofluorescence microscopy.LAPTM4A has been identified as an interaction partner of hOCT2. LAPTM4A regulates the function of hOCT2 by influencing its trafficking to/from the cell membrane and processing it via the intracellular sorting machinery. |
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