| Catalog No. | Size | Price (USD) |
| 12455-MM04-1 | 1 mL | $1,377.43 |
| 12455-MM04-20 | 20 µL | $88.87 |
| 12455-MM04-50 | 50 µL | $147.96 |
| 12455-MM04-100 | 100 µL | $251.64 |
| 12455-MM04-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-LMAN2 Antibody, Mouse Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human LMAN2 |
| Immunogen | Recombinant Human LMAN2 Protein (Catalog#12455-H08E) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LMAN2 (rh LMAN2; Catalog#12455-H08E; Q12907; Asp45-Arg322). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG2b Clone #04 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-C5orf8 Antibody; Anti-GP36B Antibody; Anti-VIP36 Antibody
Background Information
| Full Name | lectin, mannose binding 2 |
| Description | LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans-Golgi network-to-endosome transport of GPRC5B. A Golgi-traversing pathway for the exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux, respectively. |
| References |
|
title: LMAN2 promotes breast cancer progression and deduces cell sensitivity to doxorubicin through stearoyl-CoA desaturase.
authors: Changjiao Yan; Fengqiang Cui; ...; Ting Wang
journal: Breast cancer research : BCR
date: 2026-07-08
pmid: 42421146
doi: 10.1186/s13058-026-02343-3
cited_by_count: 0
techniques: CCK-8 Assay; Control; Incubation; SDS Page; Western Blot
bioz_score: 94
