| Catalog No. | Size | Price (USD) |
| 100952-T46-50 | 50 µL | $147.96 |
| 100952-T46-100 | 100 µL | $251.64 |
| 100952-T46-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-MEK3/MAP2K3 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Mouse |
| Specificity | Human, Mouse |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human MAP2K3/MKK3 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human MAP2K3/MKK3, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MAPKK3 Antibody; Anti-MEK3 Antibody; Anti-MKK3 Antibody; Anti-PRKMK3 Antibody; Anti-SAPKK-2 Antibody; Anti-SAPKK2 Antibody; Anti-SKK2 Antibody
Image / Experimental Information
| Image 1 Description | Anti-MAP2K3 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:39 kDa Observed band size:39 kDa |
| Image 1 Alt Text | Human MEK3 / MKK3 Western blot (WB) 20178 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-MAP2K3 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:39 kDa Observed band size:39 kDa |
| Image 2 Alt Text | Human MEK3 / MKK3 Immunohistochemistry(IHC) 20179 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-MAP2K3 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:39 kDa Observed band size:39 kDa |
| Image 3 Alt Text | Human MEK3 / MKK3 Immunohistochemistry(IHC) 20180 |
| Image 3 URL | Source image |
| Image 4 Description | Anti-MAP2K3 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:39 kDa Observed band size:39 kDa |
| Image 4 Alt Text | Human MEK3 / MKK3 Immunohistochemistry(IHC) 20181 |
| Image 4 URL | Source image |
| Image 5 Description | Anti-MAP2K3 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:39 kDa Observed band size:39 kDa |
| Image 5 Alt Text | Human MEK3 / MKK3 Immunohistochemistry(IHC) 20182 |
| Image 5 URL | Source image |
Background Information
| Full Name | mitogen-activated protein kinase kinase 3 |
| Description | MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3, also known as MKK3) is a Protein Coding gene. The protein encoded by this gene is a dual-specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress and participates in the MAP kinase-mediated signaling cascade. 3 alternatively spliced human isoforms have been reported. MAP2K3 is widely expressed in bone marrow, gall bladder, and other tissues. MAP2K3 resides in a biological pathway linked to memory. It is in a signaling cascade associated with beta-amyloid mediated apoptosis and has enriched expression in microglia.MAP2K3 may represent a novel therapeutic target for age-related memory decline and perhaps Alzheimer's disease (AD). |
| Related Pathways |
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