| Catalog No. | Size | Price (USD) |
| 11945-MM10-1 | 1 mL | $1,377.43 |
| 11945-MM10-20 | 20 µL | $88.87 |
| 11945-MM10-50 | 50 µL | $147.96 |
| 11945-MM10-100 | 100 µL | $251.64 |
| 11945-MM10-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-SLAMF6 Antibody, Mouse Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human SLAMF6 |
| Immunogen | Recombinant Human Ly108 / SLAMF6 Protein (Catalog#11945-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; Catalog#11945-H08H; Q96DU3-1; Met1-Met226). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #10 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD352 Antibody; Anti-KALI Antibody; Anti-KALIb Antibody; Anti-Ly108 Antibody; Anti-NTB-A Antibody; Anti-NTBA Antibody; Anti-SF2000 Antibody; Anti-UNQ6123/PRO20080 Antibody
Background Information
| Full Name | SLAM family member 6 |
| Description | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
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