| Catalog No. | Size | Price (USD) |
| 202459-T44-50 | 50 µL | $147.96 |
| 202459-T44-100 | 100 µL | $251.64 |
| 202459-T44-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-IFT81 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Cynomolgus |
| Specificity | Human, Cynomolgus |
| Immunogen | E. coli-derived Human IFT81 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human IFT81 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CDV-1 Antibody; Anti-CDV-1R Antibody; Anti-CDV1 Antibody; Anti-CDV1R Antibody; Anti-DV1 Antibody; Anti-MGC4027 Antibody; Anti-SRTD19 Antibody
Image / Experimental Information
| Image 1 Description | Anti-IFT81 rabbit polyclonal antibody at 1:500 dilution Lane A: U-251MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:79 kDa Observed band size:79 kDa |
| Image 1 Alt Text | Human IFT81 Western blot (WB) 22426 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-IFT81 rabbit polyclonal antibody at 1:500 dilution Lane A: U-251MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:79 kDa Observed band size:79 kDa |
| Image 2 Alt Text | Human IFT81 Immunohistochemistry(IHC) 22427 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-IFT81 rabbit polyclonal antibody at 1:500 dilution Lane A: U-251MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:79 kDa Observed band size:79 kDa |
| Image 3 Alt Text | Human IFT81 Immunoprecipitation(IP) 22428 |
| Image 3 URL | Source image |
Background Information
| Description | IFT81, a core component of the IFT-B complex, involved in the bidirectional transport of ciliary proteins, has been recently implicated in syndromic ciliopathies. IFT81 is an important member of the intraflagellar transport (IFT) process during spermatogenesis and that its absence is associated with abnormal flagellum formation leading to male infertility. The expression levels of several IFT components in testes, including IFT20, IFT25, IFT27, IFT57, IFT74, and IFT88, but not IFT140, were significantly reduced in homozygous mutant mice. IFT81 plays an essential role during spermatogenesis by modulating the assembly and elongation of the sperm flagella. |
| References |
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