| Catalog No. | Size | Price (USD) |
| 11064-R403-H-100 | 100 µg | $518.39 |
General Information
| Product name | Recombinant Anti-IL-32 Antibody (HRP), Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-32 |
| Immunogen | Recombinant Human IL32 Protein (Catalog#11064-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL32 (rh IL32; Catalog#11064-H08H; NP_001012651.1; Met1-Lys131), and conjugated with horseradish-peroxidase (HRP). |
| Source | Monoclonal Rabbit IgG Clone #403 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | HRP |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Protected from prolonged exposure to light. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IL-32alpha Antibody; Anti-IL-32beta Antibody; Anti-IL-32delta Antibody; Anti-IL-32gamma Antibody; Anti-NK4 Antibody; Anti-TAIF Antibody; Anti-TAIFa Antibody; Anti-TAIFb Antibody; Anti-TAIFc Antibody; Anti-TAIFd Antibody
Background Information
| Full Name | interleukin 32 |
| Description | IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer. |
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