Anti-MRPL19 Antibody, Rabbit Polyclonal sinobiological 202097-T36

$143.00
In stock
SKU
202097-T36
Catalog No.SizePrice (USD)
202097-T36-5050 µL$147.96
202097-T36-100100 µL$251.64
202097-T36-200200 µL$355.32

General Information

Product nameAnti-MRPL19 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman MRPL19
ImmunogenE. coli-derived Human MRPL19 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human MRPL19 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-bL19m Antibody; Anti-KIAA0104 Antibody; Anti-L15mt Antibody; Anti-L19mt Antibody; Anti-MRP-L15 Antibody; Anti-MRP-L19 Antibody; Anti-MRPL15 Antibody; Anti-RLX1 Antibody; Anti-RPML15 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-MRPL19 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lane B: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 1 Alt TextHuman MRPL19 Western blot (WB) 32333
Image 1 URLSource image
Image 2 DescriptionAnti-MRPL19 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lane B: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 2 Alt TextHuman MRPL19 Immunoprecipitation(IP) 32334
Image 2 URLSource image

Background Information

Full Namemitochondrial ribosomal protein L19
DescriptionMRPL19 (Mitochondrial Ribosomal Protein L19) is a Protein Coding gene. The MRPL19 gene, located on 2p12, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog. MRPL19 belongs to the bacterial ribosomal protein bL19 family. This gene encodes a 39S subunit protein and is widely expressed in the thyroid, kidney, and other tissues. Diseases associated with MRPL19 include Reading Disorder and Dyslexia. Among its related pathways are Organelle biogenesis and maintenance and Viral mRNA Translation. Data support that MRPL19 and C2ORF3 are candidate susceptibility genes for DYX3. 243 organisms have orthologs with the human gene MRPL19.
References
  1. Paracchini S, et al. (2011) Analysis of dyslexia candidate genes in the raine cohort representing the general australian population. Genes Brain Behav 10 (2): 158-165.
  2. Mascheretti S, et al. (2018) Beyond genes: A systematic review of environmental risk factors in specific reading disorder. Res Dev Disabil 82 147-152.
  3. Anthoni H, et al. (2007) A locus on 2p12 containing the co-regulated mrpl19 and c2orf3 genes is associated to dyslexia. Hum Mol Genet 16 (6): 667-677.

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