Produced in rabbits immunized with E. coli-derived Human MRPL19 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Anti-MRPL19 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lane B: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Anti-MRPL19 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lane B: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
MRPL19 (Mitochondrial Ribosomal Protein L19) is a Protein Coding gene. The MRPL19 gene, located on 2p12, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog. MRPL19 belongs to the bacterial ribosomal protein bL19 family. This gene encodes a 39S subunit protein and is widely expressed in the thyroid, kidney, and other tissues. Diseases associated with MRPL19 include Reading Disorder and Dyslexia. Among its related pathways are Organelle biogenesis and maintenance and Viral mRNA Translation. Data support that MRPL19 and C2ORF3 are candidate susceptibility genes for DYX3. 243 organisms have orthologs with the human gene MRPL19.
References
Paracchini S, et al. (2011) Analysis of dyslexia candidate genes in the raine cohort representing the general australian population. Genes Brain Behav 10 (2): 158-165.
Mascheretti S, et al. (2018) Beyond genes: A systematic review of environmental risk factors in specific reading disorder. Res Dev Disabil 82 147-152.
Anthoni H, et al. (2007) A locus on 2p12 containing the co-regulated mrpl19 and c2orf3 genes is associated to dyslexia. Hum Mol Genet 16 (6): 667-677.