Mouse PCSK9 ELISA Kit sinobiological KIT50251

$400.00
In stock
SKU
KIT50251
Catalog No.SizePrice (USD)
KIT50251-11 KIT (96 Tests)$414.71

General Information

Product nameMouse PCSK9 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural mouse PCSK9.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity24.17 pg/mL
Assay range156.25-10000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Sample Dilution Buffer Concentrate 7. Color Reagent A 8. Color Reagent B 9. Stop Solution
Product overviewThis Mouse PCSK9 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse PCSK9 protein in Serum . It contains recombinant Mouse PCSK9, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of mouse LDLR at 30 ng/mL in a mid-range recombinant mouse PCSK9 control were assayed for interference. No significant interference was observed.

Synonyms: FH3 ELISA Kit, Mouse; HCHOLA3 ELISA Kit, Mouse; Narc1 ELISA Kit, Mouse; PC9 ELISA Kit, Mouse; Pcsk9 ELISA Kit, Mouse

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextMouse PCSK9/NARC1 ELISA Kit Standard Curve 24
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextMouse PCSK9/NARC1 ELISA Kit Specificity 174
Image 2 URLSource image

Background Information

Full Nameproprotein convertase subtilisin/kexin type 9
DescriptionProprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Research Areas
  • Serine Proteases and Regulators
References
  1. Sseidah, N.G. et al., 2003, Proc. Natl. Acad. Sci. USA. 100: 928-933.
  2. Beyer, T.P. et al., 2007, J. Lipid. Res. 48: 1488-1498
  3. Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.
  4. Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
  5. Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.

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