Mouse TROY/TNFRSF19 ELISA Kit sinobiological KIT50148

$714.00
In stock
SKU
KIT50148
Catalog No.SizePrice (USD)
KIT50148-11 Kit (96 Tests)$740.55

General Information

Product nameMouse TROY/TNFRSF19 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Mouse TNFRSF19.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity7.88 pg/mL
Assay range15.63-1000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Mouse TROY/TNFRSF19 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Mouse TROY/TNFRSF19 protein in Serum . It contains recombinant Mouse TROY/TNFRSF19, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: TAJ ELISA Kit, Mouse; TAJ-ALPHA ELISA Kit, Mouse; Tnfrsf19 ELISA Kit, Mouse; TRADE ELISA Kit, Mouse; Troy ELISA Kit, Mouse

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextMouse TNFRSF19/TROY ELISA Kit Standard Curve 128
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextMouse TNFRSF19/TROY ELISA Kit Specificity 169
Image 2 URLSource image

Background Information

Full Nametumor necrosis factor receptor superfamily, member 19
DescriptionTumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
References
  1. Hu S, et al. (1999) Characterization of TNFRSF19, a novel member of the tumor necrosis factor receptor superfamily. Genomics. 62(1): 103-7.
  2. Qiu W, et al. (2010) Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP. J Biol Chem. 285(19): 14438-49.
  3. Hisaoka T, et al. (2006) Characterization of TROY/TNFRSF19/TAJ-expressing cells in the adult mouse forebrain. Brain Res. 1110(1): 81-94.

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