| Catalog No. | Size | Price (USD) |
| 11524-MM06-1 | 1 mL | $1,377.43 |
| 11524-MM06-20 | 20 µL | $88.87 |
| 11524-MM06-50 | 50 µL | $147.96 |
| 11524-MM06-100 | 100 µL | $251.64 |
| 11524-MM06-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD28 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD28 No cross-reactivity in ELISA with Mouse CD28 Human CTLA4 Mouse CTLA4 Human B7-1 Human B7-2 Mouse B7-2 Human β-NGF Human cell lysate (293 cell line) |
| Immunogen | Recombinant Human CD28 protein (Catalog#11524-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met 1-Pro 152). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #9H6E2 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Tp44 Antibody
Background Information
| Full Name | CD28 molecule |
| Description | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. |
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| References |
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title: Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
authors: Wenjing Guo; Huabin Gao; ...; Anjia Han
journal: ACS Applied Materials & Interfaces
date: 2022-07-22
pmid: 35817627
cited_by_count: 20
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay; Incubation; Proliferation Assay; Recombinant
bioz_score: 90
