| Catalog No. | Size | Price (USD) |
| 10451-R004-1 | 1 mL | $1,969.87 |
| 10451-R004-20 | 20 µL | $118.49 |
| 10451-R004-50 | 50 µL | $177.58 |
| 10451-R004-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-SCF Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human SCF No cross-reactivity in ELISA with Mouse KITL |
| Immunogen | Recombinant Human SCF / C-kit ligand protein (Catalog#10451-H08B) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human SCF / C-kit ligand (rh SCF / C-kit ligand; Catalog#10451-H08B; P21583-1; Met1-Ala189). |
| Source | Monoclonal Rabbit IgG Clone #004 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-DCUA Antibody; Anti-DFNA69 Antibody; Anti-FPH2 Antibody; Anti-FPHH Antibody; Anti-Kitl Antibody; Anti-KL-1 Antibody; Anti-MGF Antibody; Anti-SCF Antibody; Anti-SF Antibody; Anti-SHEP7 Antibody; Anti-SLF Antibody; Anti-WS2F Antibody
Background Information
| Full Name | KIT ligand |
| Description | Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. SCF/C-kit ligand stimulates the proliferation of mast cells. This protein can augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It may act synergistically with other cytokines, probably interleukins SCF/C-kit ligand is the ligand for the tyrosine kinase receptor c-kit, which is expressed on both primitive and mature hematopoietic progenitor cells. In vitro, SCF/C-kit ligand synergizes with other growth factors, such as granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor, and interleukin-3 to stimulate the proliferation and differentiation of cells of the lymphoid, myeloid, erythroid, and megakaryocytic lineages. In vivo, SCF/C-kit also synergizes with other growth factors and has been shown to enhance the mobilization of peripheral blood progenitor cells in combination with G-CSF. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone. |
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