Human IL-21 ELISA Kit sinobiological KIT10584

$400.00
In stock
SKU
KIT10584
Catalog No.SizePrice (USD)
KIT10584-11 Kit (96 Tests)$414.71
KIT10584-55 Kit (96 Tests)$1,747.71
KIT10584-4848 Tests$266.60

General Information

Product nameHuman IL-21 ELISA Kit
SpecificityThis assay recognizes recombinant Human IL-21.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeRecombinant protein
Sensitivity18.8 pg/mL
Assay range31.25-2000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human IL-21 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-21 protein in Recombinant protein . It contains recombinant Human IL-21, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: CVID11 ELISA Kit, Human; IL-21 ELISA Kit, Human; Za11 ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman IL-21 ELISA Kit Standard Curve 39421
Image 1 URLSource image

Background Information

Full Nameinterleukin 21
DescriptionIL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).
Related Pathways
  • AKT Signaling Pathway
  • Jak-Stat Signaling Pathway
  • Autophagy Pathway
  • Common G-Chain signaling pathway
  • IL12 signaling pathway
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Coquet JM, et al. (2007) IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production. J Immunol. 178(5):2827-34.
  2. Wei L, et al. (2007) IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem. 282(48):34605-10.
  3. Parrish-Novak J, et al. (2002) Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol. 72(5):856-63. 4 Kuchen S, et al. (2007) Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. J Immunol. 179(9):5886-96.

Reviews

Write Your Own Review
You're reviewing:Human IL-21 ELISA Kit sinobiological KIT10584
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.